Efficiency Eff_syn of complex syntheses as multicomponent reactions, its algorithm and calculations based on concrete criteria

• Heiner Eckert

Beilstein J. Org. Chem. 2019, 15, 1425–1433, doi:10.3762/bjoc.15.142

• Heiner Eckert Technical University of Munich, Department of Chemistry, Lichtenbergstr. 4, D-85747 Garching, Germany 10.3762/bjoc.15.142 Abstract A synthesis efficiency algorithm, which must be based on concrete and reliable criteria, is essential for the evaluation and control of complex chemical

• are highly suitable for electronic data processing (EDP). This algorithm is also suitable as a basis for fair cost assessment of complex chemical syntheses. Keywords: efficiency; efficiency algorithm; multicomponent; overall yield; synthesis algorithm; synthesis efficiency; synthesis evaluation

• values and the arithmetic mean yam calculated as shown in Equation 3. Algorithm If you insert Equation 1 in Equation 3, and then insert this in Equation 2, you will obtain the efficiency algorithm Equation 4. This has already been described in a general manner in [2][3]. The weighting of the parallel